MS factory engineers and manufactures Cellulosic Capsule Filter products designed for simple, quick, and efficient filtration of fluids used in laboratory, pilot, and small scale production applications. The cellulosic depth media is particularly suitable for high loading liquid applications where conventional membrane filters may clog prematurely due to high particulate or colloidal content. Our cellulosic capsule filters use cleaned and bleached cellulose media with natural filter aids including kieselgur and perlite, structured in a stacked disc format to provide optimal flow and high dirt holding capacity, with no adhesives, binders, or surfactants used in the manufacturing process.
Every Cellulosic Capsule Filter from MS factory is assembled in an all polypropylene construction for excellent chemical compatibility across a broad range of aqueous solutions, biological fluids, and mild chemical solutions. The compact design of the filters with respect to the filtration area reduces hold up volume and optimizes performance, which is particularly important for laboratory and pilot scale applications where product volume is limited and every milliliter of recovery matters. Multiple pore size options are available to match specific application requirements, and the filters are offered with a variety of fitting options including sanitary TC connections and hose barb connections, as well as vent and drain options including Staubli connections for on line integrity testing. With high dirt holding capacity, low extractables, and reliable performance in high loading applications, our cellulosic capsule filters provide a dependable and cost effective filtration solution for laboratory, pilot, and small scale production applications.
While membrane filters rely on a thin porous membrane that captures particles primarily on the surface through sieving, depth filters use a thick, tortuous media matrix that captures particles throughout the depth of the media through mechanical interception, inertial impaction, diffusion, and adsorption.
This depth loading behavior allows cellulosic filters to store significantly more contaminant per unit area than membrane filters, making them ideal for high loading applications where membrane filters would clog rapidly.
The cellulosic media is structured in a stacked disc format, providing a long, tortuous flow path that maximizes particle capture throughout the media depth while maintaining consistent flow characteristics.
Cleaned and bleached cellulose fibers combined with natural filter aids such as kieselgur (diatomaceous earth) and perlite enhance filtration performance by creating a more uniform pore structure and increasing effective surface area for particle adsorption.
No adhesives, binders, or surfactants are used in the manufacturing process, minimizing extractables and ensuring clean filtration performance in sensitive applications.
Choosing the right cellulosic capsule filter involves evaluating media grade or rating, filtration area configuration, fitting style, and vent or drain option. Media grade selection depends on specific application requirements, with finer grades suitable for applications demanding higher clarification efficiency and coarser grades preferred for high loading prefiltration applications where maximum dirt holding capacity is the priority.
Single layer cellulosic capsule filters provide 1300 cm² of filtration area per 10 inch length, suitable for general clarification and prefiltration applications. Double layer cellulosic capsule filters provide 650 cm² of filtration area per 10 inch length with a staged media configuration that combines a coarser upstream layer with a finer downstream layer, providing enhanced clarification performance and more consistent filtrate quality for applications demanding higher clarity.
Fitting options include 1.5 inch TC, 0.5 inch TC, 1/2 inch hose barb, and 3/4 inch hose barb connections to match specific equipment requirements. Vent and drain options include Staubli connections for on line integrity testing and stepped hose barb connections for simple venting or draining. Our technical team can help determine the optimal media grade, filtration area configuration, fitting style, and vent or drain option based on specific application requirements, fluid characteristics, and equipment configuration.
Cellulosic capsule filters are used across prefiltration of biological fluids and process solutions before sterile filtration, secondary clarification of cell culture harvest and fermentation broths, cell culture harvest clarification to remove cells and cell debris, cell culture clarification for media and buffer preparation, protein aggregate removal to improve downstream purification performance, and general clarification of aqueous solutions and biological fluids in research and development settings. In each application, the high dirt holding capacity of cellulosic depth media provides longer service life and more consistent flow performance compared to membrane filters in high loading applications, reducing the frequency of filter changes and improving overall process efficiency.
Beyond biological and pharmaceutical applications, cellulosic capsule filters are also used in food and beverage research and development for clarification of beverages, in chemical laboratories for filtration of solutions and reagents, and in environmental laboratories for sample preparation and water analysis. The broad chemical compatibility of the all polypropylene construction and the clean filtration performance of the adhesive free cellulosic media make these filters suitable for a wide range of laboratory and pilot scale filtration applications. Whether you need a prefilter for cell culture harvest clarification in a biotech pilot plant or a general clarification filter for research and development in a laboratory setting, MS factory can provide a reliable and cost effective cellulosic capsule filter solution with factory direct pricing and technical support.
• Cellulose fibers and filter aid materials verified against material specifications and biological safety standards before entering production.
• Cellulose media cleaned and bleached using controlled processes to ensure consistent purity and low extractables performance.
• Media formation, disc stacking, capsule assembly, and final inspection performed under controlled conditions with documented process parameters.
• Each capsule undergoes dimensional inspection and integrity verification before shipment, with test results recorded against unique batch identifiers.
• All components meet USP Class VI 121 degree C biological safety specifications for plastics.
• Materials comply with FDA 21 CFR food contact regulations and EU 10/2011 directives for applicable food and beverage contact applications.
• Comprehensive quality documentation available including material compliance statements, batch traceability records, integrity test reports, USP Class VI certificates, and food contact compliance declarations.