KleanCap Cellulosic Depth Media Capsule Filter

Order KleanCap Cellulosic Depth Media Capsule Filter from MS factory when your laboratory, pilot, or small scale production process requires a depth media filter that can handle high particulate loading without premature clogging. Designed for simple, quick, and efficient filtration, this family is particularly suitable for high loading liquid applications where conventional membrane filters would clog rapidly. The compact design reduces hold up volume and optimizes product recovery, critical for applications where product volume is limited.

The cellulosic depth media is structured in a stacked disc format for optimal flow and high dirt holding capacity, with particles captured throughout the media depth rather than only on the surface. No adhesives, binders, or surfactants are used, minimizing extractables and ensuring clean filtration in sensitive applications. Multiple pore size options in all polypropylene construction provide excellent chemical compatibility. Fitting options include sanitary TC and hose barb connections, with vent and drain options including Staubli for on line integrity testing.

Technical Specifications

Construction Materials

• Filter Media: Cleaned and bleached cellulose, natural filter aid (kieselgur, perlite)

• Media Support: Polypropylene

• End Caps: Polypropylene

• Inner Core: Polypropylene

• Outer Cage: Polypropylene

Fitting and Connection Options

Media Grade and Rating Selection

Depth Media Performance Advantages

•  High dirt holding capacity. Cellulosic depth media captures particles throughout the media matrix, providing significantly higher contaminant holding capacity than membrane filters and extending service life in high loading applications.

•  No adhesives, binders, or surfactants. Manufacturing process uses no adhesives, binders, or surfactants, minimizing extractables and ensuring clean filtration performance in sensitive applications.

•  All polypropylene construction. Provides excellent chemical compatibility across a broad range of aqueous solutions, biological fluids, and mild chemical solutions.

•  Multiple fitting and vent options. Variety of fitting options including sanitary TC and hose barb connections, and vent and drain options including Staubli for on line integrity testing, provide flexibility to match specific equipment requirements.

Application Notes by Process Type

•  Prefiltration. Removes particulates, colloids, and larger contaminants before sterile filtration, extending service life of downstream membrane filters and reducing overall filtration costs.

•  Secondary clarification. Captures fine particulates and colloidal material that may pass through primary filtration, producing a clearer filtrate suitable for chromatography, ultrafiltration, or sterile filtration.

•  Cell culture harvest. Removes cells, cell debris, and particulates from harvested cell culture fluid. High dirt holding capacity and low hold up volume make KleanCap Cellulosic Depth Media Capsule Filter well suited for cell culture harvest clarification in biotech pilot plants.

•  Cell culture clarification. Provides reliable particulate removal for cell culture media and buffer clarification, protecting downstream equipment and ensuring consistent media quality.

•  Protein aggregate removal. Removes protein aggregates and particulates from protein solutions before chromatography, improving column performance and extending column life with low protein binding characteristics.

Flow Rate Performance

Toxicity and Biological Safety

All components meet USP Class VI 121 degree C biological safety specifications for plastics, supporting use in pharmaceutical, biotech, and food contact applications. This certification ensures filter materials do not leach toxic substances or cause adverse biological reactions when in contact with pharmaceutical products, biological materials, or food and beverage products.

Food Safety Compliance

Materials of construction used in the KleanCap Cellulosic series are manufactured in accordance with FDA regulations governing food and beverage contact applications as set forth in Title 21 of the Code of Federal Regulations. The cellulose media and polypropylene hardware components have been evaluated for safety in direct food contact scenarios and conform to the material safety criteria established under EU Directive 10/2011, making these filters suitable for deployment in food and beverage research, development, and small scale production environments where regulatory compliance for food contact materials is required.

Capsule Integrity

Minimum burst pressure of 123.5 psi (8.5 barg) ensures robust structural integrity with a safety margin against pressure excursions. Thermal bonding and mechanical assembly ensure consistent seal integrity. The Staubli vent option supports on line bubble point testing without removing the capsule, useful for routine quality verification and batch documentation in regulated environments.

Installation, Operation, and Changeout Guidance

•  Before installation. Inspect capsule for shipping damage, verify fitting style, media grade, and configuration match application requirements.

•  Installation. Install with correct flow orientation, tighten connections per equipment specs, secure hose barb tubing with clamps. Slowly pressurize to avoid shock, vent trapped air, flush until effluent clarity meets acceptance criteria.

•  Operation. Monitor differential pressure and flow rate. Replace when differential pressure reaches site defined terminal value or flow rate declines below acceptable levels.

•  Changeout. Capsule format simplifies removal and replacement. Record installation dates, differential pressure readings, volume processed, and replacement dates for predictive maintenance scheduling.

Quality Documentation and Factory Support

•  Quality documentation. Integrity test reports, USP Class VI biocompatibility certificates, material compliance statements, food contact compliance declarations, and full batch traceability documentation. Additional documentation packages available for qualification oriented procurement.

•  Technical support. Media grade selection, fitting and vent option configuration, flow rate and differential pressure expectation setting, and changeout interval planning based on specific fluid type and solids loading.

•  Supply and customization. In house media manufacturing and capsule assembly enable flexible batch sizes, consistent performance, and dependable delivery. OEM options include custom dimensions, connection styles, media configurations, and private label branding. KleanCap Cellulosic Depth Media Capsule Filter provide dependable performance and cost effective filtration for laboratory, pilot, and small scale production applications.

Ordering Information