Special Venting Capsule Filters (SPSVC)

Order Special Venting Capsule Filters (SPSVC) from MS factory when your process requires a dependable vent filter that provides sterile gas filtration and reliable pressure equalization for tanks, vessels, and process equipment. The SPSVC capsule filter consists of hydrophobic expanded PTFE (ePTFE) membrane, offering broad chemical compatibility, higher filter area with higher flow rate at lower pressure drop compared to conventional vent filters. All polypropylene construction with thermal bonding provides clean filtration without adhesives or binders that could contribute extractables.

The hydrophobic nature of the ePTFE membrane prevents liquid from wetting through during normal operation, essential for maintaining consistent gas flow when exposed to liquid splashes, high humidity, or foam over. The capsule format simplifies installation and replacement, and 100 percent integrity testing ensures consistent performance out of the box. With broad chemical compatibility, reliable microbial retention, and clean filtration performance, the SPSVC series provides a dependable solution for sterile gas filtration and tank venting in pharmaceutical, biotech, and food and beverage manufacturing.

Technical Specifications

Construction Materials

• Filter Membrane: PTFE

• Media Support: Polypropylene

• End Caps: Polypropylene

• Inner Core: Polypropylene

• Outer Cage: Polypropylene

• Sealing Method: Thermal Bonding

Key Venting Performance Advantages

•  100 percent integrity tested. Every SPSVC vent filter undergoes integrity testing before shipment to ensure consistent membrane integrity and reliable microbial retention performance.

•  FDA food contact compliant. Materials comply with FDA 21 CFR food contact regulations and EU 10/2011 directives for food and beverage manufacturing applications.

•  Thermal bonding construction. Media pack sealed without adhesives, binders, or surfactants, minimizing extractables and ensuring clean filtration performance in sterile process applications.

•  Non fiber releasing. Capsule designed to minimize fiber shedding during normal operation, ensuring no media fibers enter the gas stream and cause contamination.

•  Broad chemical compatibility. Hydrophobic ePTFE membrane and all polypropylene construction provide compatibility with a broad range of process gases and chemical vapors.

•  High flow at low pressure drop. Higher filter area supports higher flow rates at lower pressure drop compared to conventional vent filters, helping maintain consistent pressure equalization during rapid fill and empty operations.

Vent Filter Applications by Process Type

•  Fermenter and bioreactor venting. Provides a sterile barrier for air entering and exiting during operation, with reliable microbial retention and high flow rates at low pressure drop.

•  Formulation tank air feed and venting. Sterile air filtration for both incoming and outgoing air in pharmaceutical formulation and compounding operations.

•  RO and WFI storage tank venting. Sterile air filtration preventing microbial and particulate contamination of stored water. Hydrophobic ePTFE membrane prevents water wetting through.

•  Fermentation air feed filtration. Reliable microbial retention with high flow rates at low pressure drop for consistent aeration in fermentation processes.

•  Container purge air and aseptic packaging air. Sterile air filtration for aseptic packaging and container filling operations.

Food Safety Compliance

Wetted materials in the SPSVC vent filter series meet FDA food contact specifications as set forth in 21 CFR, and the PTFE membrane and polypropylene hardware components are recognized as safe for food contact under EU Directive 10/2011. This dual compliance supports use in food and beverage manufacturing tank venting, sterile ingredient storage vessel breathing, and aseptic packaging air filtration applications where food contact material certification is part of the customer qualification and regulatory audit process.

Toxicity and Biological Safety

All components meet USP Class VI 121 degree C biological safety specifications for plastics, supporting use in pharmaceutical, biotech, and food contact applications. This certification ensures filter materials do not leach toxic substances or cause adverse biological reactions when in contact with pharmaceutical products, biological materials, or food and beverage products.

Sanitization and Sterilization

•  Filtered Hot Water. 90 degree C (194 degree F), 30 minutes, multiple cycles, maximum 3 psid forward flow. Suitable for facilities with hot water sanitization systems, commonly used for food and beverage and pharmaceutical water applications, ensuring Special Venting Capsule Filters (SPSVC) maintain reliable performance after repeated hot water sanitization cycles.

•  Autoclave. 121 degree C (250 degree F), 30 minutes, multiple cycles. Provides a higher level of microbial kill, preferred for biopharmaceutical and clinical applications where thermal resistance of organisms is a concern.

When planning repeated sanitization or sterilization cycles, buyers should consider the cumulative effect of cycles on membrane integrity and housing materials. MS factory can provide guidance on expected cycle life based on specific sanitization parameters and operating conditions.

I ntegrity Testing and Quality Assurance

•  100 percent integrity tested. Every SPSVC vent filter undergoes 100 percent integrity testing before shipment to ensure consistent membrane integrity and reliable microbial retention. Test results are recorded against unique batch identifiers for traceability.

•  On line integrity testing. Can be configured with vent ports supporting bubble point testing without removing the filter from the housing. This allows operators to verify filter integrity before and after use, a common requirement for batch release documentation and regulatory compliance.

Installation, Operation, and Replacement Guidance

•  Before installation. Inspect capsule for shipping damage, verify connection style matches equipment.

•  Installation. Install with correct flow orientation as indicated on housing, tighten connections per equipment manufacturer specs. Slowly introduce gas to avoid pressure shock, verify no leaks at connection points. Perform pre use integrity test if required by quality system.

•  Operation. Monitor differential pressure to ensure it remains within acceptable limits. Excessive differential pressure can indicate filter clogging, liquid wetting, or improper installation.

•  Replacement. Common indicators include rising differential pressure, integrity test failure, or scheduled replacement per site SOP. Record installation and replacement dates, integrity test results, and differential pressure readings to build performance history.

Quality Documentation and Factory Support

•  Quality documentation. Integrity test reports per production batch, USP Class VI biocompatibility certificates, food contact compliance declarations, material compliance statements, and complete batch traceability records. Additional documentation packages available for qualification oriented procurement.

•  Technical support. Filter sizing, pore size selection, connection style matching, integrity test protocol setup, sanitization and sterilization cycle validation, and changeout interval planning based on specific process conditions and differential pressure targets.

•  Supply and customization. Dedicated production lines with in house membrane manufacturing and capsule assembly enable consistent batch quality and dependable delivery. OEM programs include custom dimensions, connection configurations, and private label branding. Special Venting Capsule Filters (SPSVC) provide dependable and cost effective filtration for sterile gas filtration and tank venting applications that demand reliable microbial retention and consistent pressure equalization.

Ordering Information